This manuscript, which reflects a group effort involving many of our lab members, has been published in ACS Photonics. See the link here. A GUI facilitating data analysis accompanies the manuscript for all interested users!
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Our former bachelors student Vincent Kruit has rejoined the group as Researcher, working on eukaryotic replication. Later in the year he will move with the group to Oxford. Welcome back, Vincent!
Over the past few years, our group has worked hard to find ways to extract high-quality data from integrated force-fluorescence microscopy, and we have put our findings into a toolbox for the wider community to use. This work has just been accepted by ACS Photonics. Congrats to everyone involved, and […]
Lots of exciting science and great interactions at the SMB Les Houches 2024 meeting! See the pictures below. A big thanks to everyone, including our sponsors, and we hope to see many of you from the community again in 2026! Group photo: Prize winners:
Our manuscript on how to make fully custom-sequence 10 kb DNA constructs with extrahelical features for single-molecule experiments was published in Biophysical Journal on 2 January 2024. The pdf files of the published paper can be found under our Publications tab.
On October 9 and 10, most of the lab attended the Dutch Biophysics conference in Veldhoven. Lab members presented oral and poster presentations, and enjoyed seeing the work of all the other biophysics groups.
We welcome BEP student Li Jing Hu and junior researcher Jackson Moore to our lab! We look forward to having a great time doing science together with you!
In this work, we show how diffusive motion of ORC and MCM is restricted by the presence of nucleosomes surrounding an origin of replication. The PDF will be posted on our Publications page shortly. Congrats to all involved!
We are attending the CSH meeting on Eukaryotic DNA Replication and Genome Maintenance and the EMBO workshop on DNA Topology and Topoisomerases in Genome Dynamics this coming week. Nynke, Daniel, Humberto, and Zhaowei are presenting. We are looking forward to hearing about and discussing new science!
We welcome Francisco Palmero Moya to the group as our new scientific programmer, and Xiangcheng Chen as postdoc focusing on magnetic tweezers force spectroscopy. We look forward to working together with you!